Description

Fmoc-Arg(Pmc)-Opfp is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is a critical building block for the efficient and controlled assembly of complex peptides, enabling the production of therapeutic peptides, research biochemicals, and novel materials. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in peptide chemistry and drug discovery.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected arginine derivative for the sequential coupling of amino acids.
• Therapeutic Peptide Production: For the research and development of peptide-based pharmaceuticals, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation and Labeling: Used in the synthesis of peptide tags, probes, and affinity ligands for biochemical assays and diagnostics.
• Combinatorial Chemistry Libraries: Serves as a building block for creating diverse peptide libraries for high-throughput screening in drug discovery.
• Academic and Industrial Research: Fundamental reagent for studying protein structure-function relationships, signal transduction, and molecular recognition.
• Material Science: Used in the synthesis of peptide-polymer conjugates and bio-inspired materials.

Basic Information

Product Name	Fmoc-Arg(Pmc)-Opfp
CAS No.	136013-81-5
Molecular Formula	C39H46F5N5O7S
Molecular Weight	815.88 g/mol
Synonyms	Fmoc-Arg(Pmc)-OPfp; Fmoc-L-arginine(Pmc)-OPfp ester; N-α-Fmoc-N-ω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine pentafluorophenyl ester; N-α-(9-Fluorenylmethoxycarbonyl)-N-ω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine pentafluorophenyl ester; Fmoc-Arg(Pmc)-OPfp ester; Fmoc-L-Arg(Pmc)-OPfp; Pentafluorophenyl N-α-(9-fluorenylmethoxycarbonyl)-N-ω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-argininate
EINECS	Contact for details

Quality Control

Our Fmoc-Arg(Pmc)-Opfp is manufactured under strict quality control protocols to ensure the high purity and consistency required for sensitive peptide synthesis applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.