Description

Galanin (1-19) (Human) CAS NO 136005-51-1 is a synthetic peptide fragment corresponding to the N-terminal 1-19 amino acid sequence of the endogenous human neuropeptide galanin. This compound is a critical research tool for studying the diverse biological functions of galanin, including its roles in neurotransmission, nociception, and metabolic regulation. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, endocrinology, and drug discovery programs.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies investigating galanin's effects on neuronal excitability, synaptic transmission, and behavior.
• Receptor Binding Assays: Essential for competitive binding studies to characterize the affinity and selectivity of galanin receptor (GalR1, GalR2, GalR3) ligands and antagonists.
• Pain and Analgesia Studies: Applied in preclinical models to explore the modulatory role of galanin in pain pathways and the development of novel analgesic therapeutics.
• Endocrine and Metabolic Research: Investigated for its influence on insulin secretion, feeding behavior, and energy homeostasis.
• Biochemical Standard: Serves as a high-purity calibrant in analytical techniques such as HPLC and mass spectrometry for peptide quantification and identification.
• Antibody Production & Immunoassays: Utilized as an immunogen for generating specific antibodies or as a standard in ELISA and RIA development for galanin detection.

Basic Information

Product Name	Galanin (1-19) (Human)
CAS No.	136005-51-1
Molecular Formula	C106H157N29O26S
Molecular Weight	2294.66 g/mol
Synonyms	Human Galanin (1-19); Galanin (1-19) amide, human; Galanin (human) (1-19); Galanin Fragment 1-19 (human); Galanin, N-terminal fragment (1-19); GWTLNSAGYLLGPHAVGNH; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-NH2
EINECS	Contact for details

Quality Control

Our Galanin (1-19) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.