Description

Cyclo-Bis(Alanyl-Glycyl-Prolyl-Phenylalanyl) is a synthetic cyclic tetrapeptide of significant interest in advanced biochemical and pharmaceutical research. This compound matters as a sophisticated molecular scaffold for studying peptide conformation, receptor interactions, and as a potential precursor for novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, peptide chemistry, and the development of enzyme inhibitors or bioactive probes.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a key intermediate or molecular template for developing novel peptide-based therapeutics and enzyme inhibitors.
• Biochemical Studies: Used to investigate peptide-protein interactions, conformational stability, and structure-activity relationships (SAR).
• Protease Inhibition Research: Explored as a potential inhibitor for specific proteolytic enzymes due to its constrained cyclic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for advanced synthetic chemistry and peptide methodology projects.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in peptide analysis.

Basic Information

Product Name	Cyclo-Bis(Alanyl-Glycyl-Prolyl-Phenylalanyl)
CAS No.	135755-90-7
Molecular Formula	C34H44N8O6
Molecular Weight	660.77 g/mol
Synonyms	Cyclo(-Ala-Gly-Pro-Phe-)2; Cyclo(AGPF)2; Cyclic (Ala-Gly-Pro-Phe) Dimer; 1,4-Dioxo-1,4-diazacyclohexacosane-2,5,14,17-tetrone derivative; Cyclo(L-alanyl-glycyl-L-prolyl-L-phenylalanyl) (2:1); Cyclo[Ala-Gly-Pro-Phe]₂; Cyclic Tetrapeptide AGPF Dimer
EINECS	Contact for details

Quality Control

Our Cyclo-Bis(Alanyl-Glycyl-Prolyl-Phenylalanyl) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.