Description

Boc-n-Me-Cys(Mob)-Oh CAS NO 135747-89-6 is a protected cysteine derivative, specifically an N-Boc, N-methyl cysteine with a 4-methoxybenzyl (Mob) thiol protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of modified cysteine residues into complex peptide sequences. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, peptidomimetics, and chemical biology probes. The product offers high purity and reliable performance for demanding synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of N-methyl cysteine into peptide chains.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs where cysteine modification is required for stability, activity, or conjugation.
• Peptidomimetic Design: Serves as a building block for creating non-natural peptide analogs with enhanced pharmacological properties.
• Chemical Biology & Bioconjugation: Facilitates site-specific labeling or functionalization of peptides via the protected thiol group.
• Antibody-Drug Conjugate (ADC) Linker Chemistry: Potential use in constructing specialized linkers that utilize cysteine chemistry for payload attachment.
• Research & Process Development: A valuable reagent for academic and industrial R&D exploring novel peptide structures and synthetic methodologies.

Basic Information

Product Name	Boc-n-Me-Cys(Mob)-Oh
CAS No.	135747-89-6
Molecular Formula	C₁₇H₂₅NO₅S
Molecular Weight	355.45 g/mol
Synonyms	(2R)-2-[(tert-Butoxycarbonyl)(methyl)amino]-3-[(4-methoxyphenyl)methylsulfanyl]propanoic acid; N-Boc-N-methyl-S-(4-methoxybenzyl)-L-cysteine; Boc-N-Me-Cys(Mob)-OH; Boc-N-methyl-S-p-methoxybenzyl-L-cysteine; N-(tert-Butoxycarbonyl)-N-methyl-S-(4-methoxybenzyl)-L-cysteine; Fmoc-Cys(Mob)-OH related derivative; Protected N-methyl cysteine derivative; Peptide synthesis building block Boc-Cys(Mob)-OH analog
EINECS	Contact for details

Quality Control

Our Boc-n-Me-Cys(Mob)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.