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Amylin (8-37) (Human) CAS NO 135702-23-7
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CAS No.:135702-23-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Amylin (8-37) (Human) is a bioactive peptide fragment derived from the human amylin hormone. This compound serves as a potent amylin receptor antagonist, making it a critical research tool for studying metabolic pathways, insulin secretion, and diabetes. It is essential for pharmaceutical R&D, academic research, and the development of novel therapeutic agents targeting metabolic disorders.
Application
- Pharmacological Research: Used as a selective antagonist to investigate the physiological role of amylin in glucose metabolism and satiety signaling.
- Drug Discovery: A key reference standard and tool compound in the development of new anti-diabetic and obesity treatments.
- Biochemical Assays: Employed in receptor binding studies, signal transduction research, and in vitro functional assays to characterize amylin receptor activity.
- Academic Studies: Utilized in university and institutional labs for fundamental research on endocrine regulation and peptide hormone action.
- Diagnostic Development: Acts as a component in the development and validation of diagnostic tests related to metabolic syndrome.
Basic Information
| Product Name | Amylin (8-37) (Human) |
| CAS No. | 135702-23-7 |
| Molecular Formula | C144H238N44O45S2 |
| Molecular Weight | 3293.8 g/mol |
| Synonyms | Human Amylin (8-37); Amylin Fragment 8-37; IAPP (8-37); Islet Amyloid Polypeptide (8-37); hAmylin(8-37); Diabetes-Associated Peptide (8-37); Amylin Receptor Antagonist |
| EINECS | Contact for details |
Quality Control
Our Amylin (8-37) (Human) is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to relevant quality guidelines for research-grade peptides.
Storage
Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC & MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Water Content (KF) | ≤ 5.0% |
| Acetate Content (HPLC) | ≤ 10.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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