Description

Glycyl-L-Prolyl-L-Arginyl-L-Prolyl-L-Alaninamide is a synthetic pentapeptide sequence of significant interest in biochemical and pharmaceutical research. This compound matters as a specialized building block for advanced peptide synthesis, enabling the study of protein-protein interactions and the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on cardiovascular, neurological, and metabolic drug discovery.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based drug candidates targeting specific biological pathways.
• Biochemical Assay Development: For use as a reference standard or substrate in enzymatic studies and high-throughput screening assays.
• Protease Substrate Studies: Investigating the specificity and kinetics of proteolytic enzymes, given its specific amino acid sequence.
• Cell Signaling Research: Exploring its role or mimicry in cellular communication processes related to its arginine-proline motif.
• Cosmeceutical Ingredient Research: Investigating potential applications in advanced skincare formulations for bioactive peptide delivery.
• Academic & Institutional Research: Serving as a critical reagent for fundamental studies in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Glycyl-L-Prolyl-L-Arginyl-L-Prolyl-L-Alaninamide
CAS No.	135679-88-8
Molecular Formula	C24H42N12O6
Molecular Weight	594.68 g/mol
Synonyms	GPAP-NH2; Gly-Pro-Arg-Pro-Ala-NH2; H-Gly-Pro-Arg-Pro-Ala-NH2; L-Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide; Pentapeptide GPAP; GPRPA-NH2; GPRP-Amid; 135679-88-8 (CAS Registry)
EINECS	Contact for details

Quality Control

Our Glycyl-L-Prolyl-L-Arginyl-L-Prolyl-L-Alaninamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing purity, residual solvents, and other critical parameters are provided to ensure compliance with research-grade and cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, store at 2-8°C. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Content)	≥ 97.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity	≥ 99.0% (all L-isomers)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.