Description

4-Bromo-3,5-Difluorobenzaldehyde is a versatile and high-purity aromatic aldehyde building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing difluorobenzene motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated aromatic compounds.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Functional Material Precursor: Employed in the research and production of advanced materials, including liquid crystals, organic semiconductors, and polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine substituent.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	4-Bromo-3,5-Difluorobenzaldehyde
CAS No.	135564-22-6
Molecular Formula	C7H3BrF2O
Molecular Weight	220.99 g/mol
Synonyms	3,5-Difluoro-4-bromobenzaldehyde; 4-Bromo-3,5-difluorobenzaldehyde; Benzaldehyde, 4-bromo-3,5-difluoro-; 4-Bromo-3,5-difluoro-benzaldehyde; 135564-22-6; 4-Br-3,5-F2C6H2CHO
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3,5-Difluorobenzaldehyde is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. Our commitment to quality assurance supports compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.