Description

Hirudin (53-64), Rgd- is a specific, high-purity peptide fragment derived from the potent natural thrombin inhibitor, hirudin. This compound matters for its role as a critical research tool and a potential precursor in pharmaceutical development, specifically targeting platelet aggregation and thrombosis pathways. It is primarily needed by biotechnology and pharmaceutical R&D teams focused on cardiovascular disease, anticoagulant therapies, and biochemical assay development.

Application

• Biochemical Research: Used as a specific inhibitor in studies of thrombin activity, platelet aggregation, and blood coagulation cascades.
• Pharmaceutical R&D: Serves as a key reference standard and building block in the development of novel antithrombotic and anticoagulant agents.
• Diagnostic Assay Development: Employed in the calibration and validation of in-vitro diagnostic tests for hemostasis and thrombosis.
• Cell Biology Studies: Utilized to investigate cell adhesion and signaling pathways mediated by integrin receptors.
• Peptide Synthesis: Acts as a starting material or intermediate for the custom synthesis of longer peptide sequences with targeted biological activity.

Basic Information

Product Name	Hirudin (53-64), Rgd-
CAS No.	135546-62-2
Molecular Formula	C58H95N19O19
Molecular Weight	1322.5 g/mol
Synonyms	Hirudin Fragment 53-64; RGD-Hirudin(53-64); H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH; Arg-Gly-Asp (RGD) containing Hirudin peptide; Thrombin inhibitor peptide (53-64); PEG-Hirudin(53-64) precursor; Hirudin C-terminal fragment analog; Anticoagulant peptide fragment
EINECS	Contact for details

Quality Control

Our Hirudin (53-64), Rgd- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.