Description

Hirudin (53-64) CAS NO 135546-61-1 is a specific, high-purity synthetic peptide fragment derived from the natural anticoagulant protein hirudin. This compound is critical for research and development in the fields of hematology and thrombosis, serving as a potent and selective direct thrombin inhibitor. It is an essential biochemical tool for pharmaceutical companies, academic research institutions, and diagnostic kit manufacturers focused on cardiovascular diseases and anticoagulant therapies.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of blood coagulation mechanisms, platelet aggregation, and thrombosis models.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the R&D of novel anticoagulant and antithrombotic drugs.
• Diagnostic Reagents: Employed in the formulation of in vitro diagnostic assays and kits for measuring thrombin activity or screening for coagulation disorders.
• Biochemical Tool: Acts as a specific inhibitor in enzymatic assays to study thrombin's role in various physiological and pathological processes beyond coagulation.
• Quality Control: Utilized as a purity standard in the quality assurance processes for related pharmaceutical products and biotechnological preparations.

Basic Information

Product Name	Hirudin (53-64)
CAS No.	135546-61-1
Molecular Formula	C62H89N19O21
Molecular Weight	1404.5 g/mol
Synonyms	Hirudin Fragment 53-64; [1-12]-Hirudin (53-64); H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH; Thrombin Inhibitor Peptide (53-64); Hirudin (53-64) peptide; HV2 (53-64); Recombinant Hirudin Fragment
EINECS	Contact for details

Quality Control

Our Hirudin (53-64) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.