Description

Argipressin, β-Mercapto-Beta, β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Lysnh2(9)- is a synthetic analogue of the neurohypophysial hormone vasopressin, engineered for enhanced receptor selectivity and metabolic stability. This compound is critical for advanced research in endocrinology and for the development of novel therapeutic agents targeting vasopressin receptor pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on cardiovascular, renal, and central nervous system disorders.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) in preclinical studies for vasopressin receptor agonists/antagonists.
• Endocrinology Studies: Investigating the physiological roles of vasopressin in water retention, blood pressure regulation, and social behavior.
• Therapeutic Agent Development: Serving as a lead compound for creating novel treatments for conditions like diabetes insipidus, septic shock, and certain bleeding disorders.
• Biochemical Assay Standard: Used in receptor binding assays, functional cell-based tests, and analytical method development to ensure accuracy and reproducibility.
• Peptide Chemistry & Conjugation: Acting as a model compound for studying disulfide bridge formation, peptide stability, and conjugation techniques due to its modified structure.

Basic Information

Product Name	Argipressin, β-Mercapto-Beta, β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Lysnh2(9)-
CAS No.	135484-51-4
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid), 2-O-methyltyrosine, 9-lysineamide]vasopressin; d(CH2)5[Tyr(Me)^2,Lys^8]VP; Desmopressin analogue; Vasopressin V1a receptor antagonist; β-Mercapto-β,β-cyclopentamethylenepropionyl1-Tyr(Me)2-Lys-NH28-vasopressin; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid,2-O-methyltyrosine,8-lysineamide]vasopressin; Manning compound; Selective V1a antagonist.
EINECS	Contact for details

Quality Control

Our Argipressin analogue is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider under an inert atmosphere to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Maximum Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.