Description

Neuromedin C, Leu(9)-Psi-(Ch2Nh)-Leu(10)- CAS NO 135467-88-8 is a synthetic peptide analog of the neuropeptide neuromedin C, featuring a reduced peptide bond (Psi-(CH2NH)) substitution between leucine residues 9 and 10. This modification enhances its metabolic stability and receptor binding affinity, making it a critical tool for advanced biomedical research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neurobiology, oncology, and gastrointestinal physiology.

Application

• Biomedical Research: Used as a potent and stable agonist for studying bombesin receptor subtype 2 (BB2) signaling pathways and functions.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics targeting cancers and metabolic disorders.
• In Vitro & In Vivo Studies: Employed in cell-based assays and animal models to investigate the role of neuromedin C in cell proliferation, smooth muscle contraction, and satiety regulation.
• Diagnostic Reagent Development: Utilized in the formulation of high-sensitivity assay kits and diagnostic tools for receptor profiling.
• Neuroscience & Pharmacology: A key reagent for exploring the central and peripheral nervous system effects of bombesin-like peptides.

Basic Information

Product Name	Neuromedin C, Leu(9)-Psi-(Ch2Nh)-Leu(10)-
CAS No.	135467-88-8
Molecular Formula	C57H86N16O13
Molecular Weight	1187.4 g/mol
Synonyms	Neuromedin C (8-10), [Leu9-ψ(CH2NH)-Leu10]-; [ψ(CH2NH)9,10]Neuromedin C; GRP(18-20), [Leu9-ψ(CH2NH)-Leu10]-; Reduced Peptide Bond Neuromedin C Analog; Leu-ψ-(CH2NH)-Leu Neuromedin C; Pseudopeptide Neuromedin C; Bombesin Receptor Agonist Analog; NMC analog
EINECS	Contact for details

Quality Control

Our Neuromedin C analog is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.