Description

2-Chloro-4-(1H-Imidazol-1-Yl)-6-Methylpyrimidine CAS NO 135052-25-4 is a high-purity heterocyclic building block featuring a pyrimidine core substituted with chloro and imidazolyl groups. This compound is a critical intermediate in the synthesis of complex molecules, valued for its versatility in constructing pharmacologically active scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced fungicides and herbicides due to its bioactive heterocyclic structure.
• Chemical Research & Development: Serves as a versatile precursor for creating diverse chemical libraries in medicinal chemistry.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced organic materials.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Chloro-4-(1H-Imidazol-1-Yl)-6-Methylpyrimidine
CAS No.	135052-25-4
Molecular Formula	C8H7ClN4
Molecular Weight	194.62 g/mol
Synonyms	2-Chloro-4-(imidazol-1-yl)-6-methylpyrimidine; 6-Methyl-2-chloro-4-(1H-imidazol-1-yl)pyrimidine; 4-(1H-Imidazol-1-yl)-2-chloro-6-methylpyrimidine; 2-Chloro-4-imidazol-1-yl-6-methyl-pyrimidine; 135052-25-4; 2-Chloro-4-(1H-imidazol-1-yl)-6-methylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1H-Imidazol-1-Yl)-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.