Description

Gastric Inhibitory Polypeptide (1-30) Amide (Porcine) is a bioactive synthetic peptide fragment corresponding to the first 30 amino acids of the porcine Gastric Inhibitory Polypeptide (GIP), with a C-terminal amide modification. This compound is a critical research tool for studying the physiological roles of GIP, particularly its insulinotropic effects and involvement in metabolic regulation. It is essential for researchers and developers in pharmaceutical R&D, metabolic disease research, and peptide biochemistry, providing a high-purity reference standard for assay development and mechanistic studies.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting type 2 diabetes, obesity, and metabolic syndrome.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (e.g., ELISA, RIA) and receptor binding assays to quantify GIP levels or study GIP receptor (GIPR) interactions.
• Metabolic & Endocrine Studies: Applied in in vitro and in vivo research to investigate the incretin effect, insulin secretion, glucagon suppression, and lipid metabolism mediated by GIP.
• Peptide Chemistry & Analog Synthesis: Acts as a key starting material or template for the synthesis of GIP analogs, agonists, and antagonists to explore structure-activity relationships (SAR).
• Academic & Preclinical Research: Utilized in university and institutional labs for fundamental research into gastrointestinal physiology, hormone action, and nutrient sensing pathways.
• Quality Control & Standardization: Employed as a certified reference material (CRM) for quality control testing of related pharmaceutical products and diagnostic kits.

Basic Information

Item	Detail
Product Name	Gastric Inhibitory Polypeptide (1-30) Amide (Porcine)
CAS No.	134846-93-8
Molecular Formula	C149H238N44O46
Molecular Weight	3350.8 g/mol
Synonyms	GIP (1-30) amide, porcine; Glucose-dependent Insulinotropic Polypeptide (1-30) amide; Porcine GIP (1-30)-NH2; Gastric Inhibitory Peptide (1-30) amide; GIP 1-30 amide (pig); Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-NH2; H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-NH2
EINECS	Contact for details

Quality Control

Our Gastric Inhibitory Polypeptide (1-30) Amide (Porcine) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from multiple orthogonal methods including HPLC for purity, mass spectrometry (MS) for identity and molecular weight confirmation, and amino acid analysis (AAA). We adhere to high standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95% (Area Percent)
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.