Description

Butyloxycarbonyl-Cyclo(Glutamyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester is a protected cyclic peptide derivative, serving as a critical synthetic intermediate in advanced organic and peptide chemistry. Its primary value lies in enabling the controlled synthesis of complex peptide sequences, offering researchers a reliable building block for drug discovery and biochemical studies. This compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic agents, diagnostic tools, and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides and peptidomimetics.
• Drug Discovery Research: Used in medicinal chemistry programs to create novel peptide-based candidates for targeting various diseases.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in imaging, diagnostics, and target identification studies.
• Academic & Contract Research: Fundamental reagent for studying peptide structure-activity relationships (SAR) and developing new synthetic methodologies.
• Biochemical Tool Development: Used to synthesize specific peptide sequences for use as enzyme substrates, inhibitors, or receptor ligands in assay development.

Basic Information

Product Name	Butyloxycarbonyl-Cyclo(Glutamyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester
CAS No.	134790-35-5
Molecular Formula	C31H50N6O11
Molecular Weight	682.77 g/mol
Synonyms	Boc-cyclo(Glu-Pro-Asn-Lys)-OMe; Boc-Cyclo(EPNK)-OMe; Cyclo(L-glutamyl-L-prolyl-L-asparaginyl-L-lysyl) N6-(tert-butoxycarbonyl), methyl ester; Methyl N6-[(1,1-dimethylethoxy)carbonyl]-cyclo(L-α-glutamyl-L-prolyl-L-α-asparaginyl-L-lysinyl); Cyclo(Glutamyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester, N6-Boc-protected; 134790-35-5; Boc-cyclo[Glu-Pro-Asn-Lys]-OMe
EINECS	Contact for details

Quality Control

Our Butyloxycarbonyl-Cyclo(Glutamyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the product label/COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.