Description

n-[[4-(5-Bromopyrimidin-2-Yl)Oxy-3-Methyl-Phenyl]Carbamoyl]-2-Dimethyl Amino-Benzamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on oncology, antiviral, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted small-molecule drugs.
• Oncology Research: Used in the development of kinase inhibitors and other anti-cancer compounds due to its bromopyrimidine core.
• Antiviral Drug Development: Serves as a building block for novel antiviral agents targeting specific viral enzymes.
• Medicinal Chemistry & Lead Optimization: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP-compliant API production.
• Biochemical Research: Employed in biochemical assays and as a tool compound for probing biological pathways.

Basic Information

Product Name	n-[[4-(5-Bromopyrimidin-2-Yl)Oxy-3-Methyl-Phenyl]Carbamoyl]-2-Dimethyl Amino-Benzamide
CAS No.	134742-19-1
Molecular Formula	C21H20BrN5O3
Molecular Weight	470.33 g/mol
Synonyms	2-Dimethylamino-N-({4-[(5-bromopyrimidin-2-yl)oxy]-3-methylphenyl}carbamoyl)benzamide; 2-(Dimethylamino)-N-({4-[(5-bromopyrimidin-2-yl)oxy]-3-methylphenyl}carbamoyl)benzamide; N-[[4-(5-Bromopyrimidin-2-yl)oxy-3-methylphenyl]carbamoyl]-2-(dimethylamino)benzamide; Benzamide, N-[[4-[(5-bromo-2-pyrimidinyl)oxy]-3-methylphenyl]carbamoyl]-2-(dimethylamino)-; 134742-19-1; UNII-1V2R9J4W0N
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to strict internal quality management protocols suitable for pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.