Description

Aspartyl-2,3-Methanoproline Propyl Ester is a specialized synthetic amino acid derivative with a constrained proline-like structure. This compound is valued for its role as a key chiral intermediate and building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, particularly in the creation of novel peptide-based therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly protease inhibitors and other bioactive peptides.
• Peptidomimetics Research: Used in medicinal chemistry to develop constrained peptide analogs with enhanced metabolic stability and receptor selectivity.
• Flavor Enhancer Precursor: Serves as a potential precursor in the research and development of high-intensity sweeteners and savory flavor compounds.
• Biochemical Tool Compound: Employed in biochemical assays and as a standard for analytical method development in amino acid analysis.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereoselective organic synthesis reactions.

Basic Information

Product Name	Aspartyl-2,3-Methanoproline Propyl Ester
CAS No.	134732-59-5
Molecular Formula	C13H22N2O5
Molecular Weight	286.33 g/mol
Synonyms	L-Aspartyl-2,3-methanoproline propyl ester; (S)-1-[(S)-2-(Propoxycarbonyl)-3,4-methanopyrrolidin-1-yl]-1-oxo-3-aminopropan-2-ylammonium; 2,3-Methanoproline, L-aspartyl-, propyl ester; Aspartame analog; Constrained aspartame derivative; Amino acid ester derivative
EINECS	Contact for details

Quality Control

Our Aspartyl-2,3-Methanoproline Propyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.