Description

L-Alanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Isoleucyl- CAS NO 134716-88-4 is a protected dipeptide derivative, specifically an Fmoc-protected amino acid building block. This compound is critical for ensuring high coupling efficiency and purity in complex peptide synthesis workflows. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the production of therapeutic peptides, peptide hormones, and research biochemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the sequential assembly of peptides using Fmoc-chemistry protocols.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a component for creating peptide tags or linkers for protein labeling and antibody-drug conjugates (ADCs).
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships (SAR).
• Biochemical Research: Utilized in academic and industrial labs to study peptide structure, function, and interactions.
• Custom Peptide Service: A fundamental raw material for contract manufacturing organizations (CMOs) offering bespoke peptide synthesis.

Basic Information

Product Name	L-Alanine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Isoleucyl- CAS NO 134716-88-4
CAS No.	134716-88-4
Molecular Formula	C24H26N2O5
Molecular Weight	422.47 g/mol
Synonyms	Fmoc-Ile-Ala-OH; Fmoc-L-Isoleucyl-L-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucyl-L-alanine; Fmoc-Isoleucine-Alanine; Fmoc-Ile-Ala; (2S)-2-[[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-methylpentanoyl]amino]propanoic acid; Fmoc-Ileu-Ala-OH; Fmoc-L-Ile-L-Ala-OH
EINECS	Contact for details

Quality Control

Our Fmoc-protected dipeptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and NMR for structural confirmation. Certificates of Analysis (COA) with detailed chromatograms are provided to ensure traceability and compliance with your research or cGMP guidelines, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.