Description

4-Hydroxy-5-Methyl-6-n-Propylpyrimidine-2-Thiol is a specialized heterocyclic organic compound that serves as a versatile building block and intermediate in advanced chemical synthesis. Its unique pyrimidine-thiol structure makes it a valuable precursor for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific molecular functionality.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymatic pathways where the pyrimidine scaffold is active.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Chelating Agent Precursor: The thiol and hydroxyl groups make it a useful starting material for creating custom ligands in coordination chemistry and catalysis.
• Fine Chemical Production: Serves as an intermediate for synthesizing dyes, pigments, and other performance chemicals requiring a tailored heterocyclic core.
• Biochemical Research: Employed in academic and industrial R&D for studying nucleotide analogs and related biochemical processes.
• Material Science: Potential monomer or additive in the development of specialized polymers with specific electronic or binding properties.

Basic Information

Product Name	4-Hydroxy-5-Methyl-6-n-Propylpyrimidine-2-Thiol
CAS No.	134694-90-9
Molecular Formula	C8H12N2OS
Molecular Weight	184.26 g/mol
Synonyms	6-Propyl-2-mercapto-5-methyl-4-pyrimidinol; 5-Methyl-6-propyl-2-thiouracil; 2-Mercapto-5-methyl-6-propyl-4-pyrimidinol; 4-Hydroxy-5-methyl-6-propyl-2-pyrimidinethiol; 4-Pyrimidinol, 2-mercapto-5-methyl-6-propyl-; 2-Thio-5-methyl-6-propyl-4-pyrimidinol; 6-n-Propyl-5-methyl-2-thiouracil; 4-Hydroxy-5-methyl-6-propylpyrimidine-2-thione
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-5-Methyl-6-n-Propylpyrimidine-2-Thiol is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for synthesis. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.