Description

Formylmethionyl-Leucyl-α-Methyl(Phenylalanine) Methyl Ester CAS NO 134574-90-6 is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel peptide-based therapeutics and as a crucial building block in medicinal chemistry. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing enzyme inhibitors, receptor modulators, and other bioactive peptide molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of inhibitors for specific proteolytic enzymes due to its modified peptide backbone.
• Medicinal Chemistry: Serves as a key scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic assays to study metabolic pathways and enzyme kinetics.
• Peptide Library Synthesis: Utilized in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• Academic & Institutional R&D: Supports basic research in biochemistry, molecular biology, and pharmacology at universities and research institutes.

Basic Information

Product Name	Formylmethionyl-Leucyl-α-Methyl(Phenylalanine) Methyl Ester
CAS No.	134574-90-6
Molecular Formula	C27H41N3O6S
Molecular Weight	535.70 g/mol
Synonyms	N-Formyl-Met-Leu-α-Me-Phe-OMe; For-Met-Leu-α-Me-Phe-OMe; Formyl-Methionyl-Leucyl-α-Methylphenylalanine Methyl Ester; N-Formyl-L-methionyl-L-leucyl-α-methyl-L-phenylalanine methyl ester; FMOC-Protected Peptide Derivative Intermediate; Tripeptide Derivative Methyl Ester; CAS 134574-90-6; α-Methylphenylalanine-containing Peptide
EINECS	Contact for details

Quality Control

Our Formylmethionyl-Leucyl-α-Methyl(Phenylalanine) Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical intermediate applications, ensuring traceability and consistency for critical R&D and pre-clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.