Description

3-(4-Nitrophenoxy)-2-(S-Glutathionyl)-1-Propanol is a specialized biochemical compound featuring a glutathione moiety linked to a nitrophenoxy propanol structure. This molecular architecture makes it a valuable intermediate and research tool in the study of glutathione metabolism, enzyme inhibition, and redox biology. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and biochemical assays.

Application

• Biochemical Research: Used as a key intermediate or substrate in enzymatic studies related to glutathione S-transferase (GST) activity and conjugation reactions.
• Pharmaceutical Development: Serves as a building block or a model compound in the synthesis of potential drug candidates targeting oxidative stress and detoxification pathways.
• Proteomics & Molecular Biology: Employed in the study of protein glutathionylation, a critical post-translational modification involved in cellular signaling and response to oxidative damage.
• Diagnostic Reagent Manufacturing: Can be utilized in formulating specialized reagents for diagnostic kits that measure glutathione-related enzyme functions.
• Antioxidant Mechanism Studies: Acts as a tool compound to investigate the role of glutathione derivatives in cellular defense mechanisms against reactive oxygen species (ROS).

Basic Information

Product Name	3-(4-Nitrophenoxy)-2-(S-Glutathionyl)-1-Propanol
CAS No.	134564-85-5
Molecular Formula	C19H27N4O10S
Molecular Weight	503.50 g/mol
Synonyms	2-(S-Glutathionyl)-3-(4-nitrophenoxy)-1-propanol; 3-(p-Nitrophenoxy)-2-(S-glutathionyl)-1-propanol; Glutathione-(4-nitrophenoxy)propanol adduct; S-[2-Hydroxy-3-(4-nitrophenoxy)propyl]glutathione; GSH-(4-NPP) adduct; Glutathione 4-nitrophenoxypropanol conjugate
EINECS	Contact for details

Quality Control

Our 3-(4-Nitrophenoxy)-2-(S-Glutathionyl)-1-Propanol is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.