Description

Ergotaman-3',6',18-Trione, 9,10-Dihydro-12'-Hydroxy- 2'-Methyl-5'-(Phenylmethyl)-, (2',5α,5' ,8α,10,11'α,12')-, Monomethanesulfonate (Salt) is a high-purity, complex ergot alkaloid derivative, specifically formulated as a monomethanesulfonate salt for enhanced stability and handling. This compound is of significant interest in advanced pharmaceutical research and development due to its specific structural features. It serves as a critical intermediate or reference standard for scientists working in neuropharmacology and medicinal chemistry. The product, identified by CAS No. 134526-17-3, meets the stringent requirements for purity and consistency demanded in these fields.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control of related drug substances and finished products.
• Medicinal Chemistry Research: Serves as a key synthetic intermediate or a lead compound for the development of novel therapeutics targeting neurological pathways.
• Biochemical Studies: Employed in in vitro assays to investigate receptor binding affinity, enzyme inhibition, and other pharmacological mechanisms of action.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of ergot alkaloids.
• Process Development: Acts as a benchmark in the development and optimization of synthetic routes for complex alkaloid-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ergotaman-3',6',18-Trione, 9,10-Dihydro-12'-Hydroxy- 2'-Methyl-5'-(Phenylmethyl)-, (2',5α,5' ,8α,10,11'α,12')-, Monomethanesulfonate (Salt)
CAS No.	134526-17-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione monomethanesulfonate; Dihydroergocristine methanesulfonate salt; (2',5α,5',8α,10,11'α,12')-Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, monomethanesulfonate; Dihydroergocristine mesylate; DHEC mesylate; Ergot Alkaloid Derivative Salt; 134526-17-3
EINECS	Contact for details

Quality Control

Our Ergotaman-3',6',18-Trione monomethanesulfonate salt is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from advanced techniques such as HPLC for assay and related substances, IR for identification, and loss on drying. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.