Description

2,4-Dichloro-5-Chloroquinazoline is a high-purity halogenated quinazoline derivative serving as a critical synthetic intermediate. Its value lies in its versatile reactivity, particularly as a key building block for constructing complex heterocyclic systems in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A pivotal precursor in the synthesis of various quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2,4-Dichloro-5-Chloroquinazoline
CAS No.	134517-55-8
Molecular Formula	C8H3Cl3N2
Molecular Weight	233.48 g/mol
Synonyms	5-Chloro-2,4-dichloroquinazoline; 2,4,5-Trichloroquinazoline; Quinazoline, 2,4,5-trichloro-; 2,4-Dichloro-5-chloro-quinazoline
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-5-Chloroquinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment to guarantee reproducible performance and supply chain reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.