Description

S-(2-Carboxy-1-(1H-Imidazol-4-Yl)Ethyl)Glutathione is a specialized, high-purity biochemical compound of significant interest in advanced research and development. This molecule matters as a key intermediate and reference standard in the study of glutathione metabolism, oxidative stress, and related enzymatic pathways. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and manufacturers of diagnostic reagents focused on metabolic disorders and antioxidant defense mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel drug candidates targeting oxidative stress-related diseases.
• Biochemical Reference Standard: Used as a high-purity analytical standard for the quantification and identification of glutathione derivatives in complex biological matrices via HPLC or LC-MS.
• Enzymology Studies: Employed as a substrate or inhibitor in research focused on glutathione S-transferases (GSTs) and other enzymes involved in cellular detoxification.
• Diagnostic Reagent Manufacturing: A key component in the development of diagnostic kits and assays for measuring oxidative stress markers and metabolic pathway activity.
• Academic & Institutional Research: Fundamental tool for investigating the role of modified glutathiones in cell signaling, apoptosis, and disease pathology.
• Precision Medicine & Biomarker Discovery: Supports research into personalized therapeutic approaches by studying individual variations in glutathione metabolism.

Basic Information

Product Name	S-(2-Carboxy-1-(1H-Imidazol-4-Yl)Ethyl)Glutathione
CAS No.	134381-44-5
Molecular Formula	C15H22N4O8S
Molecular Weight	418.42 g/mol
Synonyms	S-(2-Carboxy-1-(1H-imidazol-4-yl)ethyl)glutathione; Glutathione, S-(2-carboxy-1-(1H-imidazol-4-yl)ethyl)-; (2S)-2-Amino-4-[[(1R)-1-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]sulfanyl]carbonyl]-3-(carboxymethylamino)-3-oxopropyl]amino]-4-oxobutanoic acid; 4-[[2-[[(4S)-4-Amino-4-carboxy-1-oxobutyl]amino]-1-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]thio]-1,2-dioxoethyl]methylamino]-4-oxobutanoic acid; Iimidazole-glutathione conjugate; Histidine-glutathione conjugate derivative
EINECS	Contact for details

Quality Control

Our S-(2-Carboxy-1-(1H-Imidazol-4-Yl)Ethyl)Glutathione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.