Description

2-Pyrimidineacetonitrile, 4-Amino- (9Ci) is a versatile pyrimidine derivative and a key heterocyclic building block in advanced organic synthesis. This compound is crucial for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its functional groups enable precise molecular modifications. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used as a key building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: A valuable reagent for constructing complex heterocyclic frameworks in academic and industrial R&D laboratories.
• Material Science: Potential use in the synthesis of specialty polymers and organic electronic materials due to its conjugated pyrimidine core.
• Bioconjugate Chemistry: The nitrile and amino groups offer handles for further functionalization, useful in creating probes or labeled compounds.

Basic Information

Product Name	2-Pyrimidineacetonitrile, 4-Amino- (9Ci)
CAS No.	134318-72-2
Molecular Formula	C6H6N4
Molecular Weight	134.14 g/mol
Synonyms	4-Amino-2-pyrimidineacetonitrile; 4-Aminopyrimidine-2-acetonitrile; 2-(4-Aminopyrimidin-2-yl)acetonitrile; (4-Amino-2-pyrimidinyl)acetonitrile; 4-Amino-2-(cyanomethyl)pyrimidine; 2-Cyanomethyl-4-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Pyrimidineacetonitrile, 4-Amino- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.