Description

(-)-α-[Hydroxymethyl]Tyrosine is a specialized, non-proteinogenic amino acid derivative of significant interest in pharmaceutical research and development. This chiral compound serves as a critical building block for the synthesis of complex molecules, particularly in the creation of enzyme inhibitors and other bioactive agents. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity chiral intermediates for advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly enzyme inhibitors and receptor antagonists.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate tyrosine-related biochemical pathways.
• Peptide Mimetics: Incorporated into peptide analogs to modify biological activity, stability, and pharmacokinetic properties.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Diagnostic Agent Development: Potential precursor for radiolabeled compounds used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	(-)-α-[Hydroxymethyl]Tyrosine
CAS No.	134309-86-7
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	(-)-α-(Hydroxymethyl)tyrosine; (2S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid; L-α-Methyl-3-(4-hydroxyphenyl)alanine; (S)-2-Amino-2-methyl-3-(4-hydroxyphenyl)propanoic acid; NSC 339579; AT-125; Acivicin intermediate; L-(-)-α-(Hydroxymethyl)tyrosine
EINECS	Contact for details

Quality Control

Our (-)-α-[Hydroxymethyl]Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.