Description

4(3H)-Quinazolinone, 2-(4-Acetyl-1-Piperazinyl)- is a specialized heterocyclic organic compound featuring a quinazolinone core substituted with a 4-acetylpiperazinyl group. This molecular architecture makes it a valuable pharmacologically active intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting central nervous system disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Chemical Reference Standard: Used as an analytical standard in quality control and method development for pharmaceutical analysis.
• Organic Synthesis Building Block: Employed in the construction of more complex heterocyclic systems for academic and industrial research.
• Biochemical Tool Compound: Utilized in in-vitro assays to study specific biological pathways and receptor interactions.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-(4-Acetyl-1-Piperazinyl)-
CAS No.	134250-02-5
Molecular Formula	C₁₄H₁₆N₄O₂
Molecular Weight	272.31 g/mol
Synonyms	2-(4-Acetylpiperazin-1-yl)quinazolin-4(3H)-one; 2-(4-Acetyl-1-piperazinyl)-4(3H)-quinazolinone; 2-(4-Acetylpiperazino)-4-hydroxyquinazoline; 4-Hydroxy-2-(4-acetyl-1-piperazinyl)quinazoline; Quinazolin-4(3H)-one, 2-(4-acetyl-1-piperazinyl)-; 134250-02-5; 2-(4-Acetylpiperazinyl)-3H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our high-purity 4(3H)-Quinazolinone, 2-(4-Acetyl-1-Piperazinyl)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.