Description

3-Fluoro-5-Bromoaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and bromine substituents on the aromatic ring, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic amines used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifier in the production of high-performance polymers and resins with specific thermal or chemical resistance properties.
• Dyestuff & Pigment Manufacturing: Intermediate for synthesizing complex azo dyes and high-value pigments requiring halogenated aniline components.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for carbon-nitrogen and carbon-carbon bond formation.

Basic Information

Product Name	3-Fluoro-5-Bromoaniline
CAS No.	134168-97-1
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	5-Bromo-3-fluoroaniline; 3-Bromo-5-fluoroaniline; 1-Amino-3-bromo-5-fluorobenzene; 3-Fluoro-5-bromobenzenamine; Aniline, 3-bromo-5-fluoro-; 3-F-5-Br-aniline; 3F5BA; 3-Fluoro-5-bromo-phenylamine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Bromoaniline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and other relevant methods. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and bases. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	52 - 56 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.