Description

D-β-Homoglutamic Acid CAS NO 134166-71-5 is a high-purity, non-proteinogenic amino acid derivative of glutamic acid, distinguished by its specific D-configuration and extended carbon chain. This chiral building block is critical for advanced pharmaceutical research and the synthesis of complex bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery, peptide synthesis, and metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate unique structural features, influencing peptide conformation and biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis, particularly in glutamate-related processes.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in the stereoselective synthesis of complex natural products and fine chemicals.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	D-β-Homoglutamic Acid
CAS No.	134166-71-5
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(R)-2-Aminopimelic Acid; D-2-Aminoheptanedioic Acid; (R)-2-Aminoheptanedioic Acid; D-β-Homoglutamic Acid; D-2-Aminopimelic Acid; (2R)-2-Aminopimelic Acid; D-α-Aminopimelic Acid; D-β-Aminopimelic Acid
EINECS	Contact for details

Quality Control

Our D-β-Homoglutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.