Description

Glutaminyl-Valyl-Valyl-S-(3-Nitro-2-Pyridinesulfenyl)Cysteinyl-Glycinamide is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced peptide synthesis and biochemical research. Its core value lies in the S-(3-Nitro-2-Pyridinesulfenyl) protecting group, which enables selective cysteine modification and facilitates complex peptide chain assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing novel peptide-based therapeutics, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the solid-phase and solution-phase synthesis of complex therapeutic peptides targeting various diseases.
• Bioconjugation Research: Used in studies involving site-specific protein and peptide labeling due to its reactive sulfenyl protecting group.
• Protease Substrate Analog: Serves as a model substrate or inhibitor in enzymatic studies to understand protease specificity and mechanism.
• Chemical Biology Tool: Employed in the development of activity-based probes for profiling enzyme activities within complex biological systems.
• Peptide Library Construction: A valuable component in the generation of diverse peptide libraries for drug discovery and screening applications.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate labs focused on peptide chemistry and molecular biology.

Basic Information

Product Name	Glutaminyl-Valyl-Valyl-S-(3-Nitro-2-Pyridinesulfenyl)Cysteinyl-Glycinamide
CAS No.	134152-14-0
Molecular Formula	C31H47N11O10S2
Molecular Weight	813.91 g/mol
Synonyms	Gln-Val-Val-Cys(Npys)-Gly-NH2; QVV-Cys(Npys)-G-NH2; H-Gln-Val-Val-Cys(Npys)-Gly-NH2; S-(3-Nitro-2-pyridinesulfenyl)-L-cysteine containing pentapeptide amide; Nα-[(Benzyloxy)carbonyl]-L-glutaminyl-L-valyl-L-valyl-S-(3-nitro-2-pyridinylthio)-L-cysteinylglycinamide (related protected form); Npys-Cysteine Peptide
EINECS	Contact for details

Quality Control

Our Glutaminyl-Valyl-Valyl-S-(3-Nitro-2-Pyridinesulfenyl)Cysteinyl-Glycinamide is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and MS for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.