Description

Somatotropin-Releasing Hormone (1-30)-Amide, Ala(2)-Leu(15)-Nle(27)-Gaba(30)- CAS NO 134101-56-7 is a synthetic peptide analog of growth hormone-releasing hormone (GHRH) designed for enhanced stability and biological activity. This compound is critical for research and development in endocrinology, specifically for studying the mechanisms of growth hormone secretion and its therapeutic potential. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic disorders and growth-related therapies.

Application

• Pharmaceutical Research & Development: A key tool for investigating the somatotropic axis, growth hormone pulsatility, and receptor binding studies.
• Preclinical Studies: Used in animal models to evaluate the efficacy and pharmacokinetics of novel GHRH-based therapeutics for conditions like growth hormone deficiency.
• Biochemical Assay Standard: Serves as a high-purity reference standard in bioanalytical methods such as HPLC and mass spectrometry for quality control.
• Peptide Chemistry & Drug Design: A model compound for studying structure-activity relationships (SAR) due to its specific amino acid substitutions (Ala2, Leu15, Nle27, Gaba30).
• Endocrine Disorder Research: Facilitates research into metabolic syndromes, aging, and muscle-wasting diseases where growth hormone pathways are implicated.

Basic Information

Item	Detail
Product Name	Somatotropin-Releasing Hormone (1-30)-Amide, Ala(2)-Leu(15)-Nle(27)-Gaba(30)- CAS NO 134101-56-7
CAS No.	134101-56-7
Molecular Formula	C149H246N44O42
Molecular Weight	~3350.8 g/mol
Synonyms	GHRH (1-30) amide, [Ala2, Leu15, Nle27, γ-Aminobutyric acid30]-hGHRH(1-30)-NH2; Growth Hormone-Releasing Factor (1-30) amide analog; Somatocrinin (1-30) amide derivative; Ala2,Leu15,Nle27,GABA30-hGHRH(1-30)-NH2; Modified GRF (1-30); hGHRH(1-30)NH2 analog; Stabilized GHRH peptide fragment
EINECS	Contact for details

Quality Control

Our Somatotropin-Releasing Hormone (1-30)-Amide is manufactured under strict quality systems suitable for research and development. Each batch is characterized using advanced analytical techniques including HPLC, MS, and amino acid analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting compliance with internal quality standards for peptide APIs and reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak matches theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.