Description

4-Methyl-2-Thioxo-6-(3,4,5-Trimethoxyphenyl)-3,6-Dihydro-1H-Pyrimidine-5-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Heterocyclic Compound Synthesis: Serves as a versatile scaffold for constructing more complex nitrogen and sulfur-containing heterocycles.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying enzyme interactions in academic and industrial R&D.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of specialty chemicals.

Basic Information

Product Name	4-Methyl-2-Thioxo-6-(3,4,5-Trimethoxyphenyl)-3,6-Dihydro-1H-Pyrimidine-5-Carboxylic Acid Ethyl Ester
CAS No.	134074-42-3
Molecular Formula	C₁₇H₂₀N₂O₅S
Molecular Weight	364.42 g/mol
Synonyms	Ethyl 4-Methyl-2-thioxo-6-(3,4,5-trimethoxyphenyl)-1,6-dihydro-5-pyrimidinecarboxylate; 4-Methyl-2-thioxo-6-(3,4,5-trimethoxyphenyl)-3,6-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester; 6-(3,4,5-Trimethoxyphenyl)-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxylic acid ethyl ester; 1H-Pyrimidine-5-carboxylic acid, 3,6-dihydro-4-methyl-2-thioxo-6-(3,4,5-trimethoxyphenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Thioxo-6-(3,4,5-Trimethoxyphenyl)-3,6-Dihydro-1H-Pyrimidine-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.