Description

Methyl 6-Methyl-4-(3-Nitrophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily needed by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in the development of new drug candidates and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially in medicinal chemistry research.
• API Synthesis: Serves as a core scaffold for the development of new active pharmaceutical ingredients targeting various disease pathways.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new reactions and creating libraries of tetrahydropyrimidine derivatives.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production for clients.
• Fine Chemical Production: Integral in the manufacture of specialized, high-value chemicals for the life sciences sector.

Basic Information

Product Name	Methyl 6-Methyl-4-(3-Nitrophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	134074-33-2
Molecular Formula	C14H13N3O4S
Molecular Weight	319.34 g/mol
Synonyms	Methyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbomethoxy-6-methyl-4-(3-nitrophenyl)-3,4-dihydro-2(1H)-pyrimidinethione; 4-(3-Nitrophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester; 3,4-Dihydro-6-methyl-4-(3-nitrophenyl)-2-thioxo-5-pyrimidinecarboxylic acid methyl ester; Methyl 4-(3-nitrophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Methyl-4-(3-Nitrophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.