Description

1,2,3,4-Tetrahydro-5-Iodo-1,3,6-Trimethyl-2,4-Dioxopyrimidine is a halogenated pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for creating complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its unique iodinated structure enables key coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Acts as a specialized building block for constructing complex uracil and pyrimidine-based compounds in academic and industrial labs.
• Material Science: Potential application in the synthesis of organic electronic materials and specialty polymers.
• Cross-Coupling Reactions: The iodine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings.

Basic Information

Product Name	1,2,3,4-Tetrahydro-5-Iodo-1,3,6-Trimethyl-2,4-Dioxopyrimidine
CAS No.	134039-54-6
Molecular Formula	C7H9IN2O2
Molecular Weight	280.06 g/mol
Synonyms	5-Iodo-1,3,6-trimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione; 5-Iodo-1,3,6-trimethyldihydrouracil; 1,3,6-Trimethyl-5-iododihydrouracil; 5-Iodo-1,3,6-trimethyl-2,4-dioxohexahydropyrimidine; 5-Iodo-TMDU; Iodinated trimethyl dihydrouracil; TMDU-I
EINECS	Contact for details

Quality Control

Our production of 1,2,3,4-Tetrahydro-5-Iodo-1,3,6-Trimethyl-2,4-Dioxopyrimidine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. All materials are characterized by modern analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.