Description

H-Pro-Leu-Gly-Nh2 H2O is a synthetic tripeptide derivative, specifically a hydrated form of the H-Pro-Leu-Gly-NH₂ sequence. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a peptide fragment and potential modulator of biological activity. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in neuroscience, peptide synthesis, and drug discovery.

Application

• Neuroscience Research: Investigation of peptide interactions with neurological receptors and pathways.
• Biochemical Reagent: Used as a standard, substrate, or intermediate in enzymatic and binding studies.
• Pharmaceutical Development: Serves as a key building block or reference compound in the synthesis and screening of novel therapeutic peptides.
• Peptide Synthesis: Acts as a protected fragment for the solid-phase or solution-phase construction of larger, more complex polypeptides.
• Cell Biology Studies: Employed in research exploring cellular signaling and communication mechanisms.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate laboratories for exploring structure-activity relationships (SAR).

Basic Information

Product Name	H-Pro-Leu-Gly-Nh2 H2O
CAS No.	134019-80-0
Molecular Formula	C₁₄H₂₆N₄O₄ • xH₂O
Molecular Weight	314.38 g/mol (anhydrous basis)
Synonyms	H-Pro-Leu-Gly-NH₂ hydrate; Pro-Leu-Glycinamide hydrate; L-Prolyl-L-leucylglycinamide hydrate; MIF-1 (Melanostatin) related peptide; PLG-NH₂ hydrate; L-Prolyl-L-leucyl-glycinamide monohydrate; Melanocyte-Inhibiting Factor-1 analog; Tripeptide H-Pro-Leu-Gly-NH₂ • H₂O
EINECS	Contact for details

Quality Control

Our H-Pro-Leu-Gly-Nh2 H2O is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from methods including HPLC, NMR, and mass spectrometry. Our quality commitment aligns with standards applicable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 8.0%
Single Impurity (HPLC)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.