Description

Neuropeptide Y, Ahx(5-24), γ-Glu(2)-ε-Lys(30)- is a synthetic peptide analog of the endogenous Neuropeptide Y (NPY), a potent neuromodulator involved in numerous physiological processes. This modified sequence is engineered for enhanced stability and specificity, making it a critical research tool for studying NPY receptor interactions, signal transduction pathways, and metabolic regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, endocrinology, and metabolic disease research.

Application

• Neuroscience Research: Investigation of NPY receptor (Y1, Y2, Y4, Y5, Y6) binding affinity, selectivity, and downstream signaling effects in the central and peripheral nervous systems.
• Metabolic Disorder Studies: Exploration of NPY's role in appetite regulation, energy homeostasis, obesity, and diabetes for potential therapeutic target identification.
• Cardiovascular Research: Study of NPY's effects on vascular tone, blood pressure, and cardiac function.
• In Vitro & Ex Vivo Assays: Use as a reference standard or active agent in cell-based assays, tissue bath experiments, and receptor autoradiography.
• Drug Discovery & Development: Serving as a lead compound or pharmacological probe for the design and screening of novel NPY receptor agonists or antagonists.
• Biochemical Characterization: Analytical standard for method development in peptide analysis using techniques like HPLC and mass spectrometry.

Basic Information

Product Name	Neuropeptide Y, Ahx(5-24), γ-Glu(2)-ε-Lys(30)-
CAS No.	133970-32-8
Molecular Formula	C₁₃₀H₂₀₃N₄₁O₃₉
Molecular Weight	2985.2 g/mol (theoretical)
Synonyms	NPY (5-24), Ahx; NPY fragment 5-24, 6-Ahx; [Ahx5-24]-NPY; Neuropeptide Y (5-24) hexanoic acid fragment; γ-Glu(2)-ε-Lys(30)-Neuropeptide Y Ahx(5-24); NPY receptor ligand analog; Synthetic NPY analog; NPY research peptide
EINECS	Contact for details

Quality Control

Every batch of our research-grade peptides undergoes rigorous analytical characterization to ensure identity, purity, and consistency. Quality is verified by multiple orthogonal methods, including reverse-phase HPLC (RP-HPLC) and mass spectrometry (MS). A comprehensive Certificate of Analysis (COA) detailing purity, molecular weight confirmation, and chromatographic data is provided with each shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.