Description

Leucine, n-(1-Oxohexyl)- is a chemically modified derivative of the essential amino acid L-Leucine, featuring a hexanoyl (caproyl) side chain. This structural modification enhances its lipophilicity, making it a valuable intermediate for the synthesis of specialized peptides, bioactive conjugates, and novel pharmaceutical compounds. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors seeking to develop products with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and prodrugs.
• Bioconjugation & Linker Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents due to its functional groups.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Cosmetic & Personal Care Actives: Potential ingredient in the formulation of advanced skincare products for enhanced delivery of active compounds.
• Material Science: Monomer or modifier for creating specialized polymers and biomaterials with specific surface properties.
• Nutritional Science Research: Investigated for its role in modified amino acid supplements and metabolic studies.

Basic Information

Product Name	Leucine, n-(1-Oxohexyl)-
CAS No.	133906-92-0
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	N-Hexanoyl-L-leucine; N-Caproyl-L-leucine; L-Leucine, N-(1-oxohexyl)-; (S)-2-(Hexanamido)-4-methylpentanoic acid; Hexanoyl leucine; Caproyl leucine; N-(1-Oxohexyl)leucine; Leucine hexanoamide acid
EINECS	Contact for details

Quality Control

Our Leucine, n-(1-Oxohexyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.