Description

2-Methoxy-6-(Trifluoromethyl)Aniline is a versatile fluorinated aromatic amine building block, distinguished by its trifluoromethyl and methoxy substituents. This compound is valued for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the creation of specialized, high-performance dyes and pigments with improved lightfastness and color properties.
• Polymer Science: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyimides and epoxy resins, to tailor thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Methoxy-6-(Trifluoromethyl)Aniline
CAS No.	133863-87-3
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-3-methoxybenzotrifluoride; 6-(Trifluoromethyl)-2-methoxyaniline; 2-Methoxy-α,α,α-trifluoro-o-toluidine; 2-Methoxy-6-trifluoromethylaniline; 2-Methoxy-6-(trifluoromethyl)benzenamine; o-Methoxy-α,α,α-trifluorotoluidine; 3-Methoxy-2-aminobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.