Description

β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid-2-Trp-8-Arg- Oxytocin CAS NO 133851-41-9 is a chemically modified, potent analog of the neuropeptide hormone oxytocin, designed for enhanced stability and receptor selectivity. This compound is critical for advanced research in neuroendocrinology and for the development of next-generation therapeutic agents targeting the oxytocin receptor pathway. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on central nervous system disorders, social behavior modulation, and novel peptide therapeutics.

Application

• Neuropharmacological Research: As a key tool compound for studying the structure-activity relationship (SAR) of oxytocin receptor (OXTR) agonists and antagonists.
• Drug Discovery & Development: Serving as a lead molecule or intermediate in the synthesis of novel peptide-based drugs for conditions like autism spectrum disorder, anxiety, and postpartum depression.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro binding assays to identify and characterize new modulators of the oxytocinergic system.
• Neuroscience Studies: Investigating the role of oxytocin pathways in social bonding, trust, stress response, and maternal behavior in animal models.
• Peptide Chemistry Reference Standard: Acting as a high-purity standard for analytical method development and quality control in peptide synthesis.
• Formulation Research: Exploring stable delivery systems for peptide hormones, leveraging its modified structure for improved pharmacokinetic profiles.

Basic Information

Product Name	β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid-2-Trp-8-Arg- Oxytocin
CAS No.	133851-41-9
Molecular Formula	C52H74N14O12S2
Molecular Weight	1111.36 g/mol
Synonyms	[Mpa1, D-Arg8]-Oxytocin; 1-(3-Mercaptopropanoic acid)-2-(tryptophan)-8-(D-arginine)-oxytocin; Deamino-2-O-tryptophan-8-D-arginine-vasotocin; β-Mercapto-beta,β-cyclopentamethylenepropionic acid-2-tryptophan-8-arginine-oxytocin; Oxytocin analog [Mpa1, D-Arg8]; Atosiban Impurity; OT Receptor Ligand; 133851-41-9
EINECS	Contact for details

Quality Control

Our β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid-2-Trp-8-Arg- Oxytocin is manufactured under strict quality systems suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for peptide research materials, and custom synthesis to specific purity grades (e.g., >95%, >98%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.