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Mivacurium CAS NO 133814-19-4


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CAS No.:133814-19-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Mivacurium is a non-depolarizing neuromuscular blocking agent belonging to the benzylisoquinolinium class. It is valued for its rapid onset and short to intermediate duration of action, making it a critical agent for controlled muscle relaxation during surgical procedures. This compound is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development organizations in the anesthesia and critical care sectors.

Application

  • Pharmaceutical Active Ingredient (API): Core component in the formulation of injectable neuromuscular blocking agents for general anesthesia.
  • Surgical Anesthesia: Used to facilitate endotracheal intubation and provide skeletal muscle relaxation during various surgical operations.
  • Intensive Care Unit (ICU) Sedation: Aids in muscle relaxation for mechanically ventilated patients requiring prolonged paralysis.
  • Pharmacological Research: Serves as a reference standard and key intermediate in studies related to neuromuscular transmission and anesthetic drug development.
  • Analytical Standard: Used in quality control laboratories for method development and validation, including HPLC and mass spectrometry assays.

Basic Information

Product Name Mivacurium
CAS No. 133814-19-4
Molecular Formula C58H80N2O14
Molecular Weight 1029.3 g/mol
Synonyms Mivacurium Chloride; BW B1090U; Mivacron; (1R,1'R,2S,2'S)-2,2'-(3,11-Dioxo-4,10-dioxatridecamethylene)bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium) Dichloride; MiVacurium; 2,2'-[Pentane-1,5-diylbis[oxy(3-oxopropane-1,3-diyl)]]bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium)
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Quality Control

Our Mivacurium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling to ensure it meets stringent pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing specifications such as HPLC purity, residual solvent content, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference standard
Identification (HPLC) Retention time matches reference
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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