Description

2-Amino-4,6-Difluorophenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and fluorine substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to impart enhanced thermal stability, chemical resistance, and specific surface properties.
• Dye & Pigment Manufacturing: Serves as an intermediate for synthesizing high-performance, light-fast dyes and pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and developing novel heterocyclic compounds.

Basic Information

Product Name	2-Amino-4,6-Difluorophenol
CAS No.	133788-83-7
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	4,6-Difluoro-2-aminophenol; 2-Amino-4,6-difluorophenol; 4,6-Difluoro-2-hydroxyaniline; 2-Hydroxy-4,6-difluoroaniline; 2-Amino-4,6-difluoro-1-hydroxybenzene; 1-Amino-3,5-difluoro-2-hydroxybenzene; Phenol, 2-amino-4,6-difluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-4,6-Difluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.