Description

Argipressin (4-8) is a synthetic peptide fragment of the neurohypophysial hormone arginine vasopressin, identified by CAS number 133761-86-1. This compound is a critical research tool for studying vasopressin receptor interactions, signal transduction pathways, and central nervous system functions. It is essential for pharmaceutical R&D, academic research, and the development of diagnostic assays targeting the vasopressin system.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of vasopressin receptor agonists and antagonists.
• Biochemical Assays: Serves as a key ligand in receptor binding studies, competitive inhibition assays, and functional activity tests for V1a and V1b receptor subtypes.
• Neuroscience Studies: Employed in research investigating the role of vasopressin in social behavior, stress response, memory, and autonomic regulation.
• Diagnostic Development: Utilized in the production and calibration of immunoassay kits for measuring vasopressin-related biomarkers.
• Peptide Chemistry: Acts as a building block or model compound for studying peptide stability, formulation, and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	Argipressin (4-8)
CAS No.	133761-86-1
Molecular Formula	C34H56N12O10S2
Molecular Weight	857.02 g/mol
Synonyms	Argipressin fragment 4-8; AVP(4-8); [Cyt6]-AVP(4-8); Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (cyclic 1-6 disulfide); Vasopressin (4-8) fragment; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (disulfide bridge); Cyclo(1-6)-[Cys1,Cys6]-AVP(4-8)
EINECS	Contact for details

Quality Control

Our Argipressin (4-8) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.