Description

Pagoclone is a high-purity pharmaceutical intermediate and research chemical of significant interest in the development of anxiolytic and neurological therapeutics. Its primary value lies in its role as a precursor or active pharmaceutical ingredient (API) in advanced pharmaceutical research and development. This compound is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis and study of novel therapeutic agents targeting the central nervous system.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced anxiolytic drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new neurological treatments.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Utilized in studies investigating GABA receptor modulation and related neurological pathways.
• Process Development & Scale-up: Critical for optimizing synthetic routes and scaling production from lab to pilot plant.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Pagoclone
CAS No.	133737-32-3
Molecular Formula	C23H26ClN3O3
Molecular Weight	427.92 g/mol
Synonyms	Pagoclone; (S)-Pagoclone; 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1,2,4-oxadiazolidin-5-one; IP-456; RP-62955; Cyclopyrrolone derivative; Anxiolytic agent IP-456
EINECS	Contact for details

Quality Control

Our Pagoclone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet rigorous pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.