Description

Poly(Arg, Pro, Thr) Hydrochloride is a synthetic polypeptide derivative composed of the amino acids arginine, proline, and threonine in its hydrochloride salt form. This compound is valued for its role as a model peptide in biochemical research and as a key intermediate in the development of specialized biomaterials and pharmaceutical agents. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on peptide synthesis, structure-activity relationship (SAR) studies, and advanced drug delivery systems.

Application

• Biochemical Research: Serves as a standard or model compound for studying peptide conformation, stability, and interactions in aqueous and biological systems.
• Pharmaceutical Development: Acts as a critical intermediate or building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biomaterial Engineering: Used in the design and testing of peptide-based hydrogels, coatings, and scaffolds for tissue engineering and regenerative medicine.
• Cell Culture & Diagnostics: May be employed as a component in specialized cell culture media or as a reagent in diagnostic assay development.
• Cosmeceutical Formulations: Investigated for potential use in advanced skincare products targeting specific biological pathways.

Basic Information

Product Name	Poly(Arg, Pro, Thr) Hydrochloride
CAS No.	133552-00-8
Molecular Formula	(C9H17N5O2 • C5H9NO2 • C4H9NO3)n • xHCl
Molecular Weight	Variable (Polymer)
Synonyms	Poly(Arginine, Proline, Threonine) HCl; Poly(RPT) Hydrochloride; (Arg-Pro-Thr)n•HCl; Poly[L-arginyl-L-prolyl-L-threonine] hydrochloride; Poly(APT) Hydrochloride; Synthetic Polypeptide Hydrochloride (Arg/Pro/Thr); Poly(L-Arg-L-Pro-L-Thr)•HCl
EINECS	Contact for details

Quality Control

Our Poly(Arg, Pro, Thr) Hydrochloride is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as amino acid composition, peptide content, residual solvents, and purity is provided with every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (Peptide Content)	≥ 95.0% (by HPLC)
Amino Acid Ratio (Arg:Pro:Thr)	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.