Description

Sar-Arg-Gly-Asp-Ser-Pro CAS NO 133525-11-8 is a synthetic hexapeptide featuring the Arg-Gly-Asp (RGD) cell adhesion motif, a sequence recognized for its critical role in mediating cell attachment and signaling. This compound is of significant value in biochemical and pharmaceutical research for studying integrin-mediated processes, including cell migration, angiogenesis, and tumor metastasis. It is primarily utilized by researchers and developers in the life sciences, biotechnology, and pharmaceutical industries for applications in drug discovery, biomaterial surface functionalization, and as a reference standard in analytical studies.

Application

• Biomedical Research: As a key tool for investigating integrin receptor binding, cell adhesion mechanisms, and signal transduction pathways in vitro.
• Drug Discovery & Development: Serving as a lead compound or a competitive inhibitor in screening assays for novel anti-thrombotic, anti-angiogenic, or anti-cancer therapeutics.
• Biomaterial Engineering: Functionalizing surfaces of implants, scaffolds, and medical devices to promote specific cellular interactions and improve biocompatibility.
• Diagnostic Assay Development: Used in the development of ELISA and other immunoassays to detect and quantify integrin binding activity.
• Cell Culture & Tissue Engineering: Coating cultureware to enhance attachment and growth of specific cell types, such as endothelial or stem cells.
• Reference Standard: Acting as a high-purity analytical standard for quality control and method validation in peptide synthesis and characterization (HPLC, MS).

Basic Information

Product Name	Sar-Arg-Gly-Asp-Ser-Pro
CAS No.	133525-11-8
Molecular Formula	C24H41N11O9
Molecular Weight	627.66 g/mol
Synonyms	Sarcosyl-Arginyl-Glycyl-Aspartyl-Seryl-Proline; Sar-RGDSP; H-Sar-Arg-Gly-Asp-Ser-Pro-OH; Cyclo(-RGDfV) related peptide; RGD-containing hexapeptide; Arg-Gly-Asp-Ser-Pro peptide derivative; Cell adhesion peptide; Integrin binding peptide
EINECS	Contact for details

Quality Control

Our Sar-Arg-Gly-Asp-Ser-Pro is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.