Description

Parathyroid Hormone [Asp76]-Human: Fragment 64-84 is a synthetic peptide fragment corresponding to a specific sequence of the human parathyroid hormone (PTH). This high-purity reference standard is critical for research and development in endocrinology and metabolic bone disease studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for applications such as bioactivity assays, antibody production, and method validation.

Application

• Biomedical Research: Used as a reference standard in studies of calcium homeostasis, bone metabolism, and parathyroid hormone receptor (PTH1R) signaling pathways.
• Pharmaceutical Development: Serves as a critical reagent in the screening and characterization of novel therapeutics targeting osteoporosis and hyperparathyroidism.
• Diagnostic Assay Calibration: Employed in the development and quality control of immunoassays (e.g., ELISA, RIA) for the precise measurement of PTH-related analytes.
• Antibody Production: Acts as a specific immunogen for generating monoclonal or polyclonal antibodies with high affinity for the PTH(64-84) region.
• Structure-Activity Relationship (SAR) Studies: Provides a defined peptide fragment for investigating the functional domains of the full-length parathyroid hormone.

Basic Information

Item	Details
Product Name	Parathyroid Hormone [Asp76]-Human: Fragment 64-84
CAS No.	133448-19-8
Molecular Formula	C115H185N35O34
Molecular Weight	~2565.9 g/mol
Synonyms	PTH (64-84), human; Parathyroid Hormone Fragment 64-84; hPTH(64-84); [Asp76]hPTH(64-84); Parathyroid hormone (64-84) (human); PTH-related peptide (64-84); H-Val-Ala-Leu-Gly-Asp-His-Asn-Phe-Val-Ala-Leu-Gly-Lys-Lys-Glu-His-Asn-Leu-Asn-OH (Asp76 variant)
EINECS	Contact for details

Quality Control

Every batch of Parathyroid Hormone [Asp76]-Human: Fragment 64-84 is manufactured under stringent conditions and subjected to comprehensive analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and development. Certificates of Analysis (COA) providing detailed results for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	±10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.