Description

For-Nle-Oh CAS NO 133388-96-2 is a high-purity, protected amino acid derivative, specifically N-Formyl-L-norleucine. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), where its formyl-protected α-amino group allows for precise and sequential chain elongation. It is an essential raw material for research institutions and pharmaceutical companies developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A key reagent in the synthesis of complex peptides and proteins for research and development.
• Pharmaceutical Research: Used in the discovery and development of peptide drugs targeting various diseases.
• Bioconjugation: Acts as a precursor for creating peptide tags and linkers used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Tool Development: Employed in the production of enzyme substrates, inhibitors, and other bioactive peptides for biochemical assays.
• Academic Research: Utilized in university and institutional labs for studying protein structure, function, and peptide chemistry.
• Custom Peptide Service Providers: A fundamental raw material for companies offering bespoke peptide manufacturing services.

Basic Information

Product Name	For-Nle-Oh
CAS No.	133388-96-2
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	N-Formyl-L-norleucine; (S)-2-Formamidohexanoic acid; F-Nle-OH; N-For-Nle-OH; L-Norleucine, N-formyl-; N-Formylnorleucine; Formyl-L-norleucine; Nα-Formyl-L-norleucine
EINECS	Contact for details

Quality Control

Every batch of For-Nle-Oh is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for peptide synthesis. A Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and identity confirmation is supplied with each shipment. Our quality protocols are designed to support cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.