Description

Neuropeptide Y (1-27) CAS NO 133361-35-0 is a specific, truncated fragment of the full-length Neuropeptide Y (NPY) hormone, consisting of its first 27 amino acids. This peptide is a critical research tool for investigating the structure-activity relationships and signaling pathways of NPY, which is a potent regulator of numerous physiological processes. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on neuroscience, metabolic disorders, and cardiovascular research.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of NPY receptor binding, neuronal communication, and behaviors related to stress, anxiety, and appetite regulation.
• Pharmacological Studies: Serves as a key intermediate or analog in the development and screening of novel therapeutics targeting Y-family receptors for conditions like obesity and epilepsy.
• Biochemical Assay Development: Employed in the calibration and validation of immunoassays (ELISA, RIA) and other analytical methods designed to detect and quantify NPY levels.
• Academic & Institutional Research: Provides a defined, high-purity compound for basic scientific investigations into peptide hormone function and signal transduction mechanisms.
• Diagnostic Reagent Manufacturing: Acts as a critical raw material in the production of antibodies, test kits, and calibration standards for clinical and research diagnostics.

Basic Information

Product Name	Neuropeptide Y (1-27)
CAS No.	133361-35-0
Molecular Formula	C152H231N43O44
Molecular Weight	3295.7 g/mol
Synonyms	NPY (1-27); Neuropeptide Y Fragment 1-27; Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-NH2; Human, rat Neuropeptide Y (1-27); [Tyr27]Neuropeptide Y (1-27); NPY 1-27 amide
EINECS	Contact for details

Quality Control

Our Neuropeptide Y (1-27) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, peptide content, and solvent residues to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This material is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. Aliquot into single-use vials to minimize freeze-thaw cycles and exposure to air.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.