Description

Phenol, 2-(1,1-Dimethylethyl)-6-Fluoro- is a specialized fluorinated phenolic compound that serves as a valuable intermediate in advanced organic synthesis. Its unique structure, featuring both a tert-butyl group and a fluorine atom on the phenol ring, makes it a critical building block for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where precise chemical functionality is required.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated phenolic moieties to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated monomers used in liquid crystal displays (LCDs) and other specialty electronic materials.
• Polymer Modification: Acts as a functional monomer or additive to introduce fluorine and phenolic groups into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for constructing complex aromatic systems and exploring new reaction pathways.

Basic Information

Product Name	Phenol, 2-(1,1-Dimethylethyl)-6-Fluoro-
CAS No.	133342-43-5
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	2-tert-Butyl-6-fluorophenol; 6-Fluoro-2-tert-butylphenol; 2-(tert-Butyl)-6-fluorophenol; 6-Fluoro-2-(1,1-dimethylethyl)phenol; 2-Fluoro-6-tert-butylphenol; 6-Fluoro-2-tert-butyl-phenol; Phenol, 2-tert-butyl-6-fluoro-; 2-tert-Butyl-6-fluoro-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Our production of Phenol, 2-(1,1-Dimethylethyl)-6-Fluoro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.