Description

1-(3,4-Dimethoxyphenethyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other specialized targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme mechanisms or biological pathways.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	1-(3,4-Dimethoxyphenethyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	133181-42-7
Molecular Formula	C₁₅H₁₅N₃O₄
Molecular Weight	301.30 g/mol
Synonyms	5-Cyano-1-(3,4-dimethoxyphenethyl)dihydrouracil; 1-(3,4-Dimethoxyphenethyl)-5-cyanodihydrouracil; 1-(3,4-Dimethoxyphenethyl)dihydro-5-cyanouracil; 1-(3,4-Dimethoxyphenethyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 1-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3,4-tetrahydro-2,4-dioxo-; Dihydrouracil-5-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dimethoxyphenethyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.