Description

2-Amino-3-(7-Methoxy-4-Coumaryl)Propionic Acid is a specialized coumarin-based amino acid derivative, serving as a critical building block and fluorescent probe in advanced chemical synthesis. Its core value lies in its unique molecular structure, which combines the photophysical properties of a methoxycoumarin fluorophore with the reactivity of an amino acid, enabling precise biochemical labeling and research. This compound is essential for researchers and manufacturers in pharmaceutical development, proteomics, and fluorescence-based assay technology, where high-purity, well-characterized intermediates are paramount for reliable results.

Application

• Fluorescent Labeling Reagent: Used as a derivatization agent for the sensitive detection and quantification of amino acids, peptides, and proteins via HPLC or capillary electrophoresis.
• Proteomics Research: Acts as a key intermediate in the synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of novel drug candidates, particularly those targeting enzymatic pathways.
• Bioconjugation: Employed to create fluorescently tagged biomolecules for cellular imaging, flow cytometry, and diagnostic assay development.
• Chemical Biology Tool: Utilized in the development of molecular sensors and reporters for real-time monitoring of biological processes.
• Reference Standard: Provides a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	2-Amino-3-(7-Methoxy-4-Coumaryl)Propionic Acid
CAS No.	133083-29-1
Molecular Formula	C₁₃H₁₃NO₅
Molecular Weight	263.25 g/mol
Synonyms	7-Methoxycoumarin-4-acetic acid β-amino acid; 2-Amino-3-(7-methoxy-2-oxo-2H-chromen-4-yl)propanoic acid; 4-Coumarylglycine derivative; AMCA-amino acid; L-7-Methoxycoumarin-4-yl-alanine (analog); Fluorescent amino acid derivative; Coumarin-based amino acid; 133083-29-1
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-(7-Methoxy-4-Coumaryl)Propionic Acid is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation (IR, NMR), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.